ANGIOFIBROMA NASOFARING BELIA PDF

Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck. The juvenile nasopharyngeal angiofibroma (JNA) is a highly Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.

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Diagnosis of JNA is made by complete history, clinical examination, radiography, nasal endoscopy; and specialized imaging techniques such as arteriography, CT, and magnetic resonance imaging MRI. Thus, early diagnosis, accurate staging, and adequate treatment are essential in the helia of this lesion. The histologic origin of JNA involves vascular nasofaribg cells or fibroblasts.

These lesions include inflammatory polyps, angiomatous polyps, nasopharyngeal cysts and carcinomas, soft tissue neoplasms such as papilloma, lymphoma, neurofibroma, maxillary malignancies, nasal fossa esthesioneuroblastoma, adenoid hypertrophy, cervical vertebrae cordomas and retropharyngeal ganglia tuberculosis.

Juvenile nasopharyngeal angiofibroma | Radiology Reference Article |

Prognosis for nasopharyngeal wngiofibroma is favorable. It presents most commonly with nasal obstruction and intermittent moderate to severe nasal bleeding. Nasopharyngeal angiofibroma also called juvenile nasopharyngeal angiofibroma [1] [2] is a histologically benign but locally aggressive vascular tumor that grows in the back of the nasal cavity.

Eur J Gen Med.

In these patients mass was encroaching on to tubal openings causing physical obstruction. The final diagnosis jasofaring achieved by histopathologic examination of tissue sections either on incisional or excisional biopsy. Extended osteoplastic maxillotomy for total excision of giant multicompartmental juvenile nasopharyngeal angiofibroma.

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JNA is benign but locally destructive. This article has been cited by other articles in PMC.

Juvenile nasopharyngeal angiofibroma JNA or nasopharyngeal angiofibroma is an uncommon fibrovascular mass arising in the nasopharynx of prepubertal and adolescent males and exhibiting a strong tendency to bleed. These discrepancies may be due to the monoclonal antibodies which detect only alpha-ER and not the beta ER protein.

Juvenile nasopharyngeal angiofibroma

Endoscopic approach to nasofafing nasopharyngeal angiofibroma: Log in Sign up. Surgical resection either open or increasingly endoscopic is the treatment of choice, usually performed with pre-operative embolisation to help with haemostasis. Numerical sex chromosome aberrations in juvenile angiofibromas: This may be attributed to a rich vasculature and lack of encapsulation.

Pancoast tumor Solitary pulmonary nodule Central lung Peripheral lung Bronchial leiomyoma.

Nasopharyngeal angiofibroma

Radiotherapy is usually reserved to patients with intracranial extension of disease where complete surgical excision may not be possible. Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck region typically affecting adolescent boys. Summary of preoperative pre-op.

Efforts to determine the pathogenesis of the tumor have been done by studying the expression of various growth factors and oncogenes such as C-KIT and C-MYC.

Please review our privacy policy. JNA being an nasofarijg tumor may recur posttreatment.

Nasopharyngeal angiofibroma – Wikipedia

According to Sessions et al. Principally four approaches were used in this study. Histopathology reveals a fibrocellular stroma with spindle cells and haphazard arrangement of collagen interspersed with an irregular vascular pattern. Any lesion with this presentation may be confused with JNA.

Contrast enhance CT scan showing JNA extending into left sphenoid sinus eroding the lateral wall of sphenoid and entering the cavernous sinus area with intracranial extradural extension. It is an aggressive neoplasm and shows a propensity for destructive local spread often extending to the base of the skull and into the cranium.

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Loss of expression of GSTM 1 null genotype is seen in this tumor. The propensity of the lesion to cause life threatening complications by way of massive bleeding has led to acquisition of considerable importance in otolaryngology practice.

Angiofibromas originating outside the nasopharynx may appear as an intraoral mass in the retromolar or buccal space area. Extraoral examination revealed normal appearing overlying skin. Patients tolerated nasal obstruction better than epistaxis. Read it at Google Books – Find it at Amazon. Adolescents and young adults between 14 and 25 years are affected, and there is a distinct angiofiboma predominance.

Connective tissue was fibro-cellular with irregular pattern and plump fibroblasts [ Figure 6 ]. Extensive bony destruction is nasofarring not a feature, but rather bone is remodelled or resorbed.

Nasal Cavity extension of JNA was seen in 10 patients with attachments to posterior end of turbinates in 8 cases and posterior end of septum in 2 patients. When diagnosed early the patients are treated with a combination of preoperative embolization and surgical resection providing a good nasofaging. Avid enhancement is noted on contrast-enhanced CT. Support Radiopaedia and see fewer ads.