Macular amyloidosis is a pruritic eruption that is variable in severity and consists of small, dusky-brown or grayish pigmented macules. Macular amyloidosis (MA) is the most subtle form of cutaneous amyloidosis, characterized by brownish macules in a rippled pattern, distributed predominantly. CASE REPORT. An unusual presentation of macular amyloidosis. Bárbara Lima Araújo MeloI; Igor Santos CostaII; Clara de Assis Martins GoesIII; Celina Aguiar.
|Country:||Turks & Caicos Islands|
|Published (Last):||4 November 2015|
|PDF File Size:||2.38 Mb|
|ePub File Size:||2.13 Mb|
|Price:||Free* [*Free Regsitration Required]|
Primary cutaneous amyloidosis PCA has an incidence that varies significantly with ethnic origin and is more common in South America and Asia than in North America and Europe. Role of friction was inconclusive.
YAG laser nm.
Histopathological findings of an amyloid deposit in the dermal papillae close to the basal layer of the epidermis confirmed the diagnosis Figure 5. Ferri’s Clinical Advisor Primary localized macular cutaneous amyloidosis: Contrary to previous reports, MA in our study was observed in a majority of patients of comparatively lighter skin than in those with a higher skin phototype.
Diffuse biphasic cutaneous amyloidosis. There’s no cure for amyloidosis.
Macular Amyloidosis (Friction Amhyloidosis)
This report describes the case of a 45year-old female presenting with hyperpigmented macules and lace-like, non-pruritic erythema in the sacral and cervical region as well as on both arms and legs. The documents contained in this web site are presented for mafular purposes only. Amyloidoses can be systemic or localized. The specific cause of your condition depends on the type of amyloidosis you have. The patient did not present with any systemic complaints, and there were no abnormal findings on physical examination other than those already described.
Amyloidosis – Symptoms and causes – Mayo Clinic
Nylon brush macular amyloidosis. Check this box if you wish to receive a copy of your message. Purpura around the eyes Some people with amyloidosis experience purpura — a condition in which small blood vessels leak blood into the skin, causing purplish patches.
In our study, there was a wide variation in the duration of the disease at the time of presentation 1 month yearsand about half of the patients presented within 2 years of appearance of the lesions. Nylon cloth macular amyloidosis. Touart, D, Sau, P. Patients can sometimes have physical findings of both lichen amyloidosis and macular amyloidosis, known as biphasic amyloidosis. Cause – effect relationship? Lichen amyloidosis associated with atopic dermatitis: Clin Endocrinol Oxf ; When signs and symptoms are evident, they depend on which of your organs are affected.
Lamina densa malformation involved in histogenesis of primary localized cutaneous amyloidosis. An association between macular amyloidosis and multiple endocrine neoplasia MEN type 2A has also been established for families presenting with hereditary forms of primary localized cutaneous amyloidosis. More studies are needed to compare different treatments and maintenance regimens.
Treatment of cutaneous amyloidoses usually yields disappointing results.
Hence, sunlight could be incriminated as a risk factor in the causation of MA in our patients. Report of a long-term study.
In cases of extensive or nodular cutaneous lesions it is important to carry out a systemic assessment. Patient education is important in breaking the itch-scratch-itch cycle. National Center for Biotechnology InformationU. An assessment of prevalence, sex, and age. Cutaneous amyloidosis associated with atopic disorders. Mesh-like pattern consisting of 6 – 10 nanometer nonbranching fibrils diagnostic of amyloid. It may also be associated with progressive systemic sclerosis, systemic lupus erythematosus, pachyonychia and other systemic diseases.
Similar observations were made amiloiosis studies by Rasi et al. You may not experience signs and symptoms of amyloidosis until the condition is advanced.
Fitzpatrick’s Dermatology in General Medicine. Approved by the Advisory Board and accepted for publication on Systemic therapies such as retinoids, cyclophosphamide, and cyclosporine have been shown to reduce pruritus and promote clearance of lesions but have more associated side effects. Intermittent use of topical dimethyl sulfoxide in macular and papular amyloidosis.
Histopathological findings aimloidosis the 26 biopsies undertaken and studied are summarized.