Limbal dermoids rank among the most common tumors of the corneal limbus. They are ocular choristomas and can occur in a variety of sizes. Images in Clinical Medicine from The New England Journal of Medicine — Limbal Dermoid. Images in Clinical Medicine from The New England Journal of Medicine — The Hairy Eyeball — Limbal Dermoid.

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Tissue sources include a pericardial graft or amniotic membrane transplantation. J Genet Hum ;1: Normal delivery at 36 weeks gestation to a year-old mother in her fourth pregnancy cermoid first three pregnancies were lost to spontaneous abortion G4 P1 SAB3.

Management of pediatric corneal limbal dermoids

Epibulbar dermoid tumours of the corneal limbus treated by lamellar keratoplasty. Genetics lijbal inheritance The pattern of inheritance is quite variable in epibulbar choristomas. A total of four eyes from group one developed a limbal stem cell deficiency within 2—16 months, resulting in a pseudopterygium formation Figure 1b.

The goal of our study was to compare the efficacy of Mitomycin C in surgical treatment of limbal dermoids. We retrospectively studied the efficacy and safety of different surgical approaches to treating pediatric limbal dermoids with regard to intra and postoperative complications.

Postoperatively, every patient showed cosmetic improvement. Lazzaro DR, Coe R. At first, the border of the limbal dermoid was limnal using a trepan or a diamond blade.


Finally a smoothing of the corneal surface was performed if necessary. He had no clefting of the lip or palate.

Management of pediatric corneal limbal dermoids

Following a comprehensive review of the published literature, our recommendations as to which surgical procedure can be best used for each grade of pediatric limbal dermoid is summarized in Table 2. They reported all but 16 eyes improved cosmetically. Surgery is universally indicated for grade II and III limbal dermoids, given that they generally cause refractive or occlusive amblyopia Table 1.

The syndrome is almost always diagnosed early in life, before there is any complaint of symptoms by the infant patient. Systemic treatment may be indicated for cardiac, renal, or CNS malformations.

dremoid Cohen J, Schanen NC. They concluded FG-assisted augmented AMT was easily performed for repairing large corneal perforations. Group dermlid included eleven eyes. Given this, surgical removal of the limbal dermoid on the left side can be postponed indefinately. Full-thickness central corneal grafts in lamellar keratoscleroplasty likbal treat limbal dermoids. The description of his initial presentation is here provided and his course of care is described in the Course section of this case presentation.

Simple and direct excision of such lesions will inevitably result in restrictive strabismus and diplopia. Surgical outcomes of epibulbar dermoids.

Chan SM, Boisjoly H. It is recommended that these children undergo close clinical observation with serial examinations in the office, not only to monitor stability but also to provide reassurance for parents.


Essentially small asymptomatic grade I limbal dermoids should not be removed because they may lead to postoperative scarring and development of pseudopterygium. Solid dermoids of the limbus and the cornea.

All surgeries were performed by the same surgeon. This was the patient’s first presentation for eye care. Follow-up ranged from 2 to 53 months median 17 months. The use of amniotic membrane transplantation in the removal of a limbal dermoid has recently been described by others. Amniotic dermoiid transplantation for ocular surface reconstruction.

Panton and Sugar reviewed the clinical files of 10 patients who had undergone simple excision of a unilateral grade I epibulbar limbal dermoid. Mitomycin C as an antitumor antibiotic was first isolated from Streptomyces caespitosus in Winces to light, both eyes OU. In addition, the patients need a longer postoperative follow-up until a final evaluation is possible. Maurice Goldenhar Goldenhar, in a pair of monozygotic twins with epibulbar dermoids, auricular appendages, malformations of the auricle, and hemifacial microsomia.